Day 031 - 05 Oct 94 - Page 07
1 country to country and, as a product of that difference in
2 distribution, he suggested that the only reason he could
3 see for this contrast in distribution was that some 30 to
4 about 70 per cent of the cause of cancer was related to
5 the diets of the different countries.
6
7 Now, nothing really was picked up on that issue because
8 the smoking issue came to the front as a consequence of
9 Sir Richard Doll's work, and it was left more or less in
10 the libraries. But it began to be rehearsed again in the
11 1970s. It was not really until the 1980s Caroll and
12 others -- I presented some of the epidemiological graphs
13 which Caroll has published -- took up the issue again. So
14 it was really the end of the 70s and the beginning of the
15 80s that the relationship between diet and cancer began to
16 become an issue.
17
18 Q. Can you go into a bit more detail about the sorts of
19 evidence that have come up since then?
20 A. The evidence again is largely epidemiological, and
21 I think my enclosure 1 presents Caroll's initial
22 publication of the country to country evidence, which is
23 very striking. It related, interestingly enough, in a
24 very similar way to the evidence in heart disease in the
25 sense that the same countries that had the high incidence
26 of cancer of the breast, colon and prostate were the same
27 countries that had the high mortalities from heart
28 disease. And you just need to glance at enclosure 1 to
29 recognise this fact.
30
31 Q. Do you want to take the court to enclosure 1? If it
32 helps, I will hold it up. It is the chart.
33 A. If you -----
34
35 MR. JUSTICE BELL: Where has that come from?
36
37 MS. STEEL: I gave you a copy of it the other day, directly
38 behind his statement.
39
40 MR. JUSTICE BELL: It is the one immediately behind the
41 supplemental statement.
42
43 MS. STEEL: Yes.
44
45 THE WITNESS: What it shows, if you look at breast cancer, is
46 that countries like Netherlands, Denmark, New Zealand,
47 United Kingdom, United States, Ireland, Australia and
48 Belgium are right at the top of the league; whereas
49 countries like Japan and Thailand are very much at the
50 bottom of the league with the Mediterranean countries
51 somewhat in the middle.
52
53 Essentially, this is the same kind of data that came out
54 of Ancell Keys' Seven Countries study, which was published
55 in the early 1950s which looked at the incidence in seven
56 different countries, including the Mediterranean, Finland,
57 United States and Japan, and, from the evidence in
58 relation to heart disease (it was mortality evidence they
59 were looking at) the conclusion was that the relationship
60 that existed between heart disease and dietary fat intake