Day 022 - 12 Sep 94 - Page 37


     
     1        A.  Yes.  In fairness though, that is actually quite a
     2        complex phenomenon and, you know, it is not only diet
     3        which changes when people move or one aspect of their diet
     4        which changes, lots of other things change when people
     5        move from an undeveloped country to a developed country.
     6
     7   Q.   But, for example, in the immediate, in the short term, it
     8        would not have any implications for genetic ---
     9        A.  It certainly would not.
    10
    11   Q.   -- links to cancer so that would be an advantage over
    12        genetic?
    13        A.  But you would have to take into the account the fact
    14        that many factors were changing, and you would need to
    15        know what the interplay of all these changing factors was.
    16
    17   Q.   Yes.   I am not an academic, or whatever, but I presume
    18        that people do their studies responsibly and take into
    19        account various -----
    20        A.  Yes, I agree.  These are worthwhile studies and it is
    21        very important to look at migrating populations.
    22
    23   Q.   Before I move on from populations studies, you have said
    24        if they are very strongly correlated, then their evidence
    25        would be more important.  If something is so strong, then
    26        it seems to leave ----
    27        A.  Well, I personally believe that the information that
    28        you get from a population study should direct you along
    29        avenues of research.  It is the pointer to the direction
    30        that you should be trying to look at to try to establish a
    31        relationship between the observed effect and possible
    32        causation.
    33
    34   Q.   Would you say that the correlations for links between diet
    35        and cancer in the population studies are very high?
    36        A.  Yes.
    37
    38   Q.   Very high.  Are they as high as, I do not know, smoking
    39        and cancer?
    40        A.  No, but it has been suggested if you just look at
    41        population studies and the differences that one sees in
    42        them ---
    43
    44   Q.   You would be convinced?
    45        A.  -- diet would account for perhaps 80 per cent of
    46        cancer incidence.
    47
    48   Q.   Right.
    49        A.  I think we have actually discussed this already.
    50 
    51   Q.   Yes.  If we deal with other ones:  You said there are 
    52        problems with animal experimentation.  Do you want to say 
    53        any more about that, what are the strengths and
    54        weaknesses?
    55        A.  Again, I think animal work does give you guidelines to
    56        conduct further research.  One of the difficulties always
    57        with animal research is knowing whether what you are doing
    58        to the animal is actually the same in the human subject.
    59        It is important to remember that a lot of these
    60        experiments are conducted on mice, for example, or rats

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